Living with suicidal thoughts every month was something Humphries had become used to.
These kinds of extreme symptoms started a week before her period when she was in what's known as the luteal phase of her menstrual cycle and for years she had believed it was completely normal.
That is, until she was diagnosed with PMDD, which could affect up to 8% of people who have periods in the UK.
''I had a lot of thoughts of about hurting myself or not wanting to be alive anymore," Humphries tells BBC News. "And I was, yeah, really in quite a dark place."
The comedian says she didn't know anything about the condition until she started to look up some of her symptoms online and was eventually diagnosed by a private doctor.
Now she's turned her experiences of living with PMDD into a stand-up routine for her show Square Peg.
The 30-year-old says sharing her experiences of it on stage has felt ''very empowering'' because she's been ''able to find the funny in some really dark times''.
"It is very personal. It's very honest, a bit raw at times, but still very funny, I think," she reflects. "And I have been told that by lots of other people."
