What Is Low-Grade Dysplasia/Dysplasia?:

What Is Low-Grade Dysplasia/Dysplasia?: en.wikipedia.org/wiki/Dysplasia

Dysplasia (from Greek, roughly: \"bad form\") is a term used in pathology to refer to an abnormality in maturation of cells within a tissue.

This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells.

Dysplasia is often indicative of an early neoplastic process.

The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early, in-situ neoplasm.

For example, epithelial dysplasia of the cervix (cervical intraepithelial neoplasia - a disorder commonly detected by an abnormal pap smear) consists of an increased population of immature (basal-like) cells which are restricted to the mucosal surface, and have not invaded through the basement membrane to the deeper soft tissues.

Myelodysplastic syndromes, or dysplasia of blood-forming cells, show increased numbers of immature cells in the bone marrow, and a decrease in mature, functional cells in the blood.

Dysplasia, in which cell maturation and differentiation are delayed, can be contrasted with metaplasia, in which cells of one mature, differentiated type are replaced by cells of another mature, differentiated type.

What Is Low-Grade Dysplasia/Dysplasia?: www.health-science-report.com/cervical-d...grade-dysplasia.html

Low Grade Dysplasia: www.health-science-report.com/cervical-d...grade-dysplasia.html

When diagnosed with low grade dysplasia, the wart virus HPV is usually detected and cryosurgery can be performed to remove the dysplastic cells.

This condition has several stages: CIN 1 (mild), CIN 2 (moderate) and CIN 3 (severe or carcinoma in situ).

Mild stages are better not to treat, especially in young girls, because the disorders are minor and the young system is able to cope with them.

When diagnosed with low grade dysplasia, the wart virus HPV is usually detected and cryosurgery can be performed to remove the dysplastic cells.

What Is Low-Grade Dysplasia/Dysplasia?: www.pi.nhs.uk/car/anomaly/skeletal/skeletaldysplasia.htm

INTRODUCTION: www.pi.nhs.uk/car/anomaly/skeletal/skeletaldysplasia.htm

Skeletal dysplasias are a heterogeneous group of congenital anomalies which affect cartilage and/or bone growth.

There are many specific syndromes which are often very precisely characterised, down to knowledge of the specific gene defect in many cases, with only subtle differences between classifications.

Individually these syndromes have a low birth prevalence.

Skeletal dysplasias are generally caused by a single gene defect and most are autosomal recessive, however some types are autosomal dominant (e.g. achondroplasia) or caused by teratogens (e.g. warfarin).

The syndromes in this group have certain features in common, and allow for a general overview of these conditions.

The long bones of the limbs and the ribs are the structures most often affected, and many of the syndromes in this group have additional features which help to make the diagnosis.

The shortening of the long bones may primarily affect the proximal bones (the femur and humerus), called rhizomelic shortening or primarily affect the distal bones (the tibia/fibula and radius/ulna), called mesomelic.

The long bones may be curved or so weak that multiple fractures occur, leading to angulation within the long bones.

What Is Low-Grade Dysplasia/Dysplasia?: Polycarpaly and other abnormalities of the wrist in chondroectodermal dysplasia: the Ellis-van Creveld syndrome: radiology.rsnajnls.org/cgi/content/abstract/151/2/393

Radiographs of 45 wrists of 23 patients who had chondroectodermal dysplasia (CED) showed variable wrist malformations, which we grouped into eight categories.

In each patient, the wrists tended to be similar but seldom identical; in six patients they were sufficiently dissimilar that we classified the malformations in their two wrists into separate categories.

A ninth carpal bone was present in the wrists of all patients who were five years old or older (42 of 45 wrists).

It was located in the distal row, medial to the hamate bone and proximal to the fifth and sixth metacarpals.

A tenth carpal bone was found in six wrists.

Unlike the ninth carpal bone, it varied in location.

All of the carpal bones were deformed, and two or three separate ossification centers of the hamate were found in some individuals.

Fusions between the capitate, the hamate, and the ninth carpal bone were present by the last available examination in 71% of the 45 hands: these included fusions between the capitate and hamate in 7%, between the hamate and the ninth carpal bone in 47%, and between all three bones in 18%.

What Is Low-Grade Dysplasia/Dysplasia?: cancerweb.ncl.ac.uk/cgi-bin/omd?skeletal+dysplasia

skeletal dysplasia: cancerweb.ncl.ac.uk/cgi-bin/omd?skeletal+dysplasia

One of a large contingent of genetic diseases in which the bony skeleton is abnormally formed during development.

For example, achondroplasia (achondroplastic dwarfism).

What Is Low-Grade Dysplasia/Dysplasia?: Skeletal Dysplasias: www.isds.ch/PDF%20Files/Adv%20Pediatrics%20Skel%20Dys.pdf